Immunocytochemical Characterization of Alzheimer’s Disease Hallmarks in APP/PS1 Transgenic Mice Treated with a New Anti-Amyloid-β Vaccine

Immunocytochemical Characterization of Alzheimer’s Disease Hallmarks in APP/PS1 Transgenic Mice Treated with a New Anti-Amyloid-β Vaccine

Introduction: APP/PS1 double-transgenic mouse models of Alzheimer’s disease (AD), which overexpress mutated forms of the gene for the human amyloid precursor protein (APP) and presenilin 1 (PS1), have provided robust neuropathological hallmarks of an AD-like pattern at early ages. This study aimed t...

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Bibliographic Details
Main Authors: Ivan Carrera, Ignacio Etcheverria, Yi Li, Lucia Fernandez-Novoa, Valter Lombardi, Carmen Vigo, Hector H. Palacios, Valery V. Benberin, Ramon Cacabelos, Gjumrakch Aliev
Format: Article
Language:English
Published: University Library System, University of Pittsburgh 2014-03-01
Series:Central Asian Journal of Global Health
Online Access:http://cajgh.pitt.edu/ojs/index.php/cajgh/article/view/119

Internet

http://cajgh.pitt.edu/ojs/index.php/cajgh/article/view/119

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