All-trans retinoic acid increases the pathogenicity of the H9N2 influenza virus in mice
Abstract Background The H9N2 virus can infect not only birds but also humans. The pathogenicity of H9N2 virus infection is determined by an excessive immune response in the lung. All-trans retinoic acid (ATRA), the active metabolite of vitamin A, plays an important regulatory role and has been widel...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-06-01
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Series: | Virology Journal |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12985-022-01809-y |