An Expeditious, Green and Protecting-Group-Free Synthesis of a Potent Secondary Metabolite Calebin-A and Its Analogues

An Expeditious, Green and Protecting-Group-Free Synthesis of a Potent Secondary Metabolite Calebin-A and Its Analogues

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Abstract The synthesis of Calebin-A (10a) and analogues (10b–d), which are minor but pharmacologically active components (<0.01% of the oleoresin) of curcuma longa, is described. This flexible synthesis is achieved under near neutral conditions in water/solvent biphasic medium at room temperature...

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Bibliographic Details
Main Authors: Anju Majeed, Kalyanam Nagabhushanam, Muhammed Majeed, Samuel Manoharan Thomas, Nooruddin Thajuddin
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2017-03-01
Series:SynOpen
Subjects:
calebin-a
curcuma longa
ferulic acid ester
phase-transfer catalyst (ptc)
green synthesis
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0036-1591507

Internet

http://www.thieme-connect.de/DOI/DOI?10.1055/s-0036-1591507

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