Reverse Electrochemical Sensing of FLT3-ITD Mutations in Acute Myeloid Leukemia Using Gold Sputtered ZnO-Nanorod Configured DNA Biosensors

Reverse Electrochemical Sensing of FLT3-ITD Mutations in Acute Myeloid Leukemia Using Gold Sputtered ZnO-Nanorod Configured DNA Biosensors

Detection of genetic mutations leading to hematological malignancies is a key factor in the early diagnosis of acute myeloid leukemia (AML). FLT3-ITD mutations are an alarming gene defect found commonly in AML patients associated with high cases of leukemia and low survival rates. Available diagnost...

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Bibliographic Details
Main Authors: Ramesh Thevendran, Kai Loong Foo, Mohd Hazwan Hussin, Emmanuel Jairaj Moses, Marimuthu Citartan, Haarindraprasad Rajintra Prasad, Solayappan Maheswaran
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Biosensors
Subjects:
acute myeloid leukemia
DNA biosensor
FLT3-ITD
Au sputtered-ZnO nanorods
electrochemical impedance spectroscopy
Online Access:https://www.mdpi.com/2079-6374/12/3/170

Internet

https://www.mdpi.com/2079-6374/12/3/170

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