Design and Characterization of Novel Antibody-Cytokine Fusion Proteins Based on Interleukin-21

Interleukin-21 (IL21) is a pleiotropic cytokine involved in the modulation of both innate and adaptive immunity. IL21 is mainly secreted by natural killer (NK) and activated CD4+ T-cells. The biology of this cytokine can be associated to proinflammatory responses reflecting its potent stimulatory ac...

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Bibliographic Details
Main Authors: Cesare Di Nitto, Dario Neri, Tobias Weiss, Michael Weller, Roberto De Luca
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Antibodies
Subjects:
Online Access:https://www.mdpi.com/2073-4468/11/1/19