The efficacy of simultaneous action of several antisense oligonucleotide derivatives by the example of lipid metabolism in mice

The efficacy of simultaneous action of several antisense oligonucleotide derivatives by the example of lipid metabolism in mice

Motivation and Aim: Demonstration of the possibility of lipid metabolism regulation by joint action of several antisense oligonucleotide derivatives (ASOs) targeted to mRNAs of closely associated proteins involved in lipid metabolism. Material and Methods: Female mice of the C57BL/6J strain; 1...

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Bibliographic Details
Main Authors: S. I. Oshevskii, Yu. I. Ragino, E. V. Kashtanova, Ya. V. Polonskaya, E. M. Stakhneva, V. P. Nikolin, N. A. Popova, A. N. Korablev, N. A. Kolchanov, M. I. Voevoda
Format: Article
Language:Russian
Published: Siberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, branch of the Institute of Cytology and Genetics 2015-09-01
Series:Атеросклероз
Subjects:
antisense oligonucleotide derivatives
lipid metabolism regulation
Online Access:https://ateroskleroz.elpub.ru/jour/article/view/768/706

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https://ateroskleroz.elpub.ru/jour/article/view/768/706

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