The mitotic spindle is chiral due to torques within microtubule bundles
Forces are required for congression of chromosomes by microtubule spindles. Here, using super-resolution microscopy and computational modelling, the authors find that in addition to forces, torques caused by the microtubule motor protein kinesin-5 induce chirality and curves into the spindle.
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2018-09-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-06005-7 |