Hypoxia-Induced Differences in the Expression of Pyruvate Dehydrogenase Kinase 1-Related Factors in the Renal Tissues and Renal Interstitial Fibroblast-like Cells of Yak (Bos Grunniens)

Hypoxia-Induced Differences in the Expression of Pyruvate Dehydrogenase Kinase 1-Related Factors in the Renal Tissues and Renal Interstitial Fibroblast-like Cells of Yak (Bos Grunniens)

Hypoxia is one of the factors severely affect renal function, and, in severe cases, it can lead to renal fibrosis. Although much progress has been made in identifying the molecular mediators of fibrosis, the mechanisms that govern renal fibrosis remain unclear, and there have been no effective thera...

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Bibliographic Details
Main Authors: Manlin Zhou, Jun Wang, Ruirui Cao, Fan Zhang, Xuehui Luo, Yiyuan Liao, Weiji Chen, Haie Ding, Xiao Tan, Zilin Qiao, Kun Yang
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Animals
Subjects:
yak
kidney
renal fibrosis
PDK1
TGF-β1/Smad signaling pathway
Online Access:https://www.mdpi.com/2076-2615/14/21/3110

Internet

https://www.mdpi.com/2076-2615/14/21/3110

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