Protein-protein interactions in clathrin vesicular assembly: radial distribution of evolutionary constraints in interfaces.

In eukaryotic organisms clathrin-coated vesicles are instrumental in the processes of endocytosis as well as intracellular protein trafficking. Hence, it is important to understand how these vesicles have evolved across eukaryotes, to carry cargo molecules of varied shapes and sizes. The intricate n...

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Podrobná bibliografie
Hlavní autoři: Rupali A Gadkari, Narayanaswamy Srinivasan
Médium: Článek
Jazyk:English
Vydáno: Public Library of Science (PLoS) 2012-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC3285160?pdf=render