β-Amyloid Fragment 25–35 Causes Mitochondrial Dysfunction in Primary Cortical Neurons
β-Amyloid deposition and compromised energy metabolism both occur in vulnerable brain regions in Alzheimer's disease. It is not known whether β-amyloid is the cause of impairment of energy metabolism, nor whether impaired energy metabolism is specific to neurons. Our results, using primary neur...
Main Authors: | C.S. Casley, J.M. Land, M.A. Sharpe, J.B. Clark, M.R. Duchen, L. Canevari |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2002-08-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996102905164 |
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