SWI/SNF Antagonism of PRC2 Mediates Estrogen-Induced Progesterone Receptor Expression

Endometrial cancer (EC) is characterized by high estrogen levels unopposed by progesterone. Treatment with progestins is standard for early EC, but the response to progestins is dependent on progesterone receptor (PGR) expression. Here, we show that the expression of PGR in endometrial epithelial ce...

Celý popis

Podrobná bibliografie
Hlavní autoři: Mike R. Wilson, Jake J. Reske, Julie Koeman, Marie Adams, Niraj R. Joshi, Asgerally T. Fazleabas, Ronald L. Chandler
Médium: Článek
Jazyk:English
Vydáno: MDPI AG 2022-03-01
Edice:Cells
Témata:
On-line přístup:https://www.mdpi.com/2073-4409/11/6/1000