Small-Medium Extracellular Vesicles and Their miRNA Cargo in Retinal Health and Degeneration: Mediators of Homeostasis, and Vehicles for Targeted Gene Therapy

Small-Medium Extracellular Vesicles and Their miRNA Cargo in Retinal Health and Degeneration: Mediators of Homeostasis, and Vehicles for Targeted Gene Therapy

Photoreceptor cell death and inflammation are known to occur progressively in retinal degenerative diseases such as age-related macular degeneration (AMD). However, the molecular mechanisms underlying these biological processes are largely unknown. Extracellular vesicles (EV) are essential mediators...

Full description

Bibliographic Details
Main Authors: Yvette Wooff, Adrian V. Cioanca, Joshua A. Chu-Tan, Riemke Aggio-Bruce, Ulrike Schumann, Riccardo Natoli
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
retina
neurodegeneration
extracellular vesicle
microRNA
immuno-modulation
gene therapy
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00160/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2020.00160/full

Similar Items