Radiation therapy induces immunosenescence mediated by p90RSK

Radiation therapy induces immunosenescence mediated by p90RSK

Radiation therapy (RT) to the chest increases the patients’ risk of cardiovascular disease (CVD). A complete understanding of the mechanisms by which RT induces CVD could lead to specific preventive, therapeutic approaches. It is becoming evident that both genotoxic chemotherapy agents and radiation...

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Bibliographic Details
Main Authors: Masaki Imanishi, Haizi Cheng, Sivareddy Kotla, Anita Deswal, Nhat-Tu Le, Eduardo Chini, Kyung Ae Ko, Venkata S. K. Samanthapudi, Ling-Ling Lee, Joerg Herrmann, Xiaolei Xu, Cielito Reyes-Gibby, Sai-Ching J. Yeung, Keri L. Schadler, Syed Wamique Yusuf, Zhongxing Liao, Roza Nurieva, El-ad David Amir, Jared K. Burks, Nicolas L. Palaskas, John P. Cooke, Steven H. Lin, Michihiro Kobayashi, Momoko Yoshimoto, Jun-ichi Abe
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
radiotherapy
immunosenescence
p90RSK
CD38
T-bet
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.988713/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2022.988713/full

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