Effects of murine and human bone marrow-derived mesenchymal stem cells on cuprizone induced demyelination.

Effects of murine and human bone marrow-derived mesenchymal stem cells on cuprizone induced demyelination.

For the treatment of patients with multiple sclerosis there are no regenerative approaches to enhance remyelination. Mesenchymal stem cells (MSC) have been proposed to exert such regenerative functions. Intravenous administration of human MSC reduced the clinical severity of experimental autoimmune...

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Main Authors: Jasmin Nessler, Karelle Bénardais, Viktoria Gudi, Andrea Hoffmann, Laura Salinas Tejedor, Stefanie Janßen, Chittappen Kandiyil Prajeeth, Wolfgang Baumgärtner, Annemieke Kavelaars, Cobi J Heijnen, Cindy van Velthoven, Florian Hansmann, Thomas Skripuletz, Martin Stangel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724887?pdf=render

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http://europepmc.org/articles/PMC3724887?pdf=render

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