Increased osteoclastogenesis in mice lacking the carcinoembryonic antigen-related cell adhesion molecule 1.

Alterations in bone remodeling are a major public health issue, as therapeutic options for widespread bone disorders such as osteoporosis and tumor-induced osteolysis are still limited. Therefore, a detailed understanding of the regulatory mechanism governing bone cell differentiation in health and...

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Bibliographic Details
Main Authors: Timo Heckt, Thomas Bickert, Anke Jeschke, Sebastian Seitz, Jochen Schulze, Wulf D Ito, Wolfgang Zimmermann, Michael Amling, Thorsten Schinke, Andrea Kristina Horst, Johannes Keller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4260834?pdf=render