Polarized Expression of p75NTR Specifies Axons during Development and Adult Neurogenesis

Newly generated neurons initiate polarizing signals that specify a single axon and multiple dendrites, a process critical for patterning neuronal circuits in vivo. Here, we report that the pan-neurotrophin receptor p75NTR is a polarity regulator that localizes asymmetrically in differentiating neuro...

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Bibliographic Details
Main Authors: Emanuela Zuccaro, Matteo Bergami, Beatrice Vignoli, Guillaume Bony, Brian A. Pierchala, Spartaco Santi, Laura Cancedda, Marco Canossa
Format: Article
Language:English
Published: Elsevier 2014-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714001533