The protein phosphatase PP6 promotes RIPK1-dependent PANoptosis
Abstract Background The innate immune system serves as the first line of host defense. Transforming growth factor-β–activated kinase 1 (TAK1) is a key regulator of innate immunity, cell survival, and cellular homeostasis. Because of its importance in immunity, several pathogens have evolved to carry...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-05-01
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Series: | BMC Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12915-024-01901-5 |