1,25-Dihydroxyvitamin D3 and 20-Hydroxyvitamin D3 Upregulate LAIR-1 and Attenuate Collagen Induced Arthritis

1,25-Dihydroxyvitamin D3 and 20-Hydroxyvitamin D3 Upregulate LAIR-1 and Attenuate Collagen Induced Arthritis

Vitamin D plays a crucial role in regulation of the immune response. However, treatment of autoimmune diseases with 1,25-dihydroxyvitamin D3 [1,25(OH)<sub>2</sub>D3] doses sufficient to be effective is prohibitive due to its calcemic and toxic effects. We use the collagen-induced arthrit...

Full description

Bibliographic Details
Main Authors: Linda K. Myers, Michael Winstead, John D. Kee, Jeoungeun J. Park, Sicheng Zhang, Wei Li, Ae-Kyung Yi, John M. Stuart, Edward F. Rosloniec, David D. Brand, Robert C. Tuckey, Andrzej T. Slominski, Arnold E. Postlethwaite, Andrew H. Kang
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
arthritis
vitamin D
20<i>S</i>(OH)D3
LAIR-1
autoimmunity
Online Access:https://www.mdpi.com/1422-0067/22/24/13342

Internet

https://www.mdpi.com/1422-0067/22/24/13342

Similar Items