Lack of association between the tagging SNP A+930-->G of SOCS3 and type 2 diabetes mellitus: meta-analysis of four independent study populations.

Lack of association between the tagging SNP A+930-->G of SOCS3 and type 2 diabetes mellitus: meta-analysis of four independent study populations.

The suppressor of cytokine signalling 3 (SOCS3) provides a link between cytokine action and their negative consequences on insulin signalling. Thus SOCS3 is a potential candidate gene for type 2 diabetes (T2DM).Based on HapMap we identified the polymorphism A+930-->G (rs4969168) as a haplotype ta...

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Bibliographic Details
Main Authors: Antje Fischer-Rosinsky, Eva Fisher, Peter Kovacs, Matthias Blüher, Matthias Möhlig, Andreas F H Pfeiffer, Heiner Boeing, Joachim Spranger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2585796?pdf=render

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http://europepmc.org/articles/PMC2585796?pdf=render

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