SUMOylation regulates USP5-Cav3.2 calcium channel interactions

SUMOylation regulates USP5-Cav3.2 calcium channel interactions

Abstract Cav3.2 calcium channels play a key role in nociceptive signaling in the primary afferent pain pathway. We have previously reported the regulation of Cav3.2 calcium channels by the deubiquitinase USP5 and its importance for regulating peripheral transmission of pain signals. Here we describe...

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Bibliographic Details
Main Authors: Agustin Garcia-Caballero, Fang-Xiong Zhang, Lina Chen, Said M’Dahoma, Junting Huang, Gerald W. Zamponi
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Molecular Brain
Subjects:
T-type
Ubiquitination
SUMOylation
USP5
Cav3.2
Calcium channel
Online Access:http://link.springer.com/article/10.1186/s13041-019-0493-9

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http://link.springer.com/article/10.1186/s13041-019-0493-9

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