The SH3 regulatory domain of the hematopoietic cell kinase Hck binds ELMO via its polyproline motif

Eukaryotic EnguLfment and cell MOtility (ELMO) proteins form an evolutionary conserved family of regulators involved in small GTPase dependent actin remodeling processes that regulates the guanine exchange factor activity of some of the Downstream Of CrK (DOCK) family members. Gathered data strongly...

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Bibliographic Details
Main Authors: Rida Awad, Marion Sévajol, Isabel Ayala, Anne Chouquet, Philippe Frachet, Pierre Gans, Jean-Baptiste Reiser, Jean-Philippe Kleman
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1016/j.fob.2015.01.009