Autophagic adaptation to oxidative stress alters peritoneal residential macrophage survival and ovarian cancer metastasis

Autophagic adaptation to oxidative stress alters peritoneal residential macrophage survival and ovarian cancer metastasis

Tumor-associated macrophages (TAMs) affect cancer progression and therapy. Ovarian carcinoma often metastasizes to the peritoneal cavity. Here, we found 2 peritoneal macrophage subsets in mice bearing ID8 ovarian cancer based on T cell immunoglobulin and mucin domain containing 4 (Tim-4) expression....

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Bibliographic Details
Main Authors: Houjun Xia, Shasha Li, Xiong Li, Weichao Wang, Yingjie Bian, Shuang Wei, Sara Grove, Weimin Wang, Linda Vatan, J. Rebecca Liu, Karen McLean, Ramandeep Rattan, Adnan Munkarah, Jun-Lin Guan, Ilona Kryczek, Weiping Zou
Format: Article
Language:English
Published: American Society for Clinical investigation 2020-09-01
Series:JCI Insight
Subjects:
Immunology
Online Access:https://doi.org/10.1172/jci.insight.141115

Internet

https://doi.org/10.1172/jci.insight.141115

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