Neutralizing monoclonal antibodies against the Gc fusion loop region of Crimean-Congo hemorrhagic fever virus.

Crimean-Congo hemorrhagic fever virus (CCHFV) is a highly pathogenic tick-borne virus, prevalent in more than 30 countries worldwide. Human infection by this virus leads to severe illness, with an average case fatality of 40%. There is currently no approved vaccine or drug to treat the disease. Neut...

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Bibliographic Details
Main Authors: Liushuai Li, Tingting Chong, Lu Peng, Yajie Liu, Guibo Rao, Yan Fu, Yanni Shu, Jiamei Shen, Qinghong Xiao, Jia Liu, Jiang Li, Fei Deng, Bing Yan, Zhihong Hu, Sheng Cao, Manli Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-02-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011948&type=printable