Autophagy Induced by Toll-like Receptor Ligands Regulates Antigen Extraction and Presentation by B Cells

Autophagy Induced by Toll-like Receptor Ligands Regulates Antigen Extraction and Presentation by B Cells

The engagement of B cells with surface-tethered antigens triggers the formation of an immune synapse (IS), where the local secretion of lysosomes can facilitate antigen uptake. Lysosomes intersect with other intracellular processes, such as Toll-like Receptor (TLR) signaling and autophagy coordinati...

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Bibliographic Details
Main Authors: Jonathan Lagos, Sara Sagadiev, Jheimmy Diaz, Juan Pablo Bozo, Fanny Guzman, Caroline Stefani, Silvana Zanlungo, Mridu Acharya, Maria Isabel Yuseff
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
B cell
antigen extraction
TLR
CpG
autophagy
αV integrin
Online Access:https://www.mdpi.com/2073-4409/11/23/3883

Internet

https://www.mdpi.com/2073-4409/11/23/3883

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