Solubility measurement and thermodynamic modeling of pantoprazole sodium sesquihydrate in supercritical carbon dioxide

Abstract Knowing the solubility data of pharmaceutical compounds in supercritical carbon dioxide (ScCO2) is essential for nanoparticles formation by using supercritical technology. In this work, solubility of solid pantoprazole sodium sesquihydrate in ScCO2 is determined and reported at 308, 318, 32...

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Bibliographic Details
Main Authors: Gholamhossein Sodeifian, Chandrasekhar Garlapati, Fariba Razmimanesh, Hassan Nateghi
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-11887-1