Pancreatic islet cell therapy for type I diabetes: understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation

<p>Abstract</p> <p>While insulin replacement remains the cornerstone treatment for type I diabetes mellitus (T1DM), the transplantation of pancreatic islets of Langerhans has the potential to become an important alternative. And yet, islet transplant therapy is limited by several f...

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Bibliographic Details
Main Authors: Li Xin, Harlan David M, Liu Eric, Wang Ena, Jin Ping, Ren Jiaqiang, Stroncek David F
Format: Article
Language:English
Published: BMC 2007-01-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/5/1/1