Selection of aptamers against triple negative breast cancer cells using high throughput sequencing

Abstract Triple-negative breast cancer is the most aggressive subtype of invasive breast cancer with a poor prognosis and no approved targeted therapy. Hence, the identification of new and specific ligands is essential to develop novel targeted therapies. In this study, we aimed to identify new apta...

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Bibliographic Details
Main Authors: Débora Ferreira, Joaquim Barbosa, Diana A. Sousa, Cátia Silva, Luís D. R. Melo, Meltem Avci-Adali, Hans P. Wendel, Ligia R. Rodrigues
Format: Article
Language:English
Published: Nature Portfolio 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87998-y