Selective Nitro Reduction of Ester Substituted Nitroarenes by NaBH4-FeCl2

Abstract This work aimed to explore a novel protocol for selective reduction of the nitro group on the aromatic ring while remaining the ester group unaffected. In this study, NaBH4-FeCl2 was disclosed as a key reductant in the process. NaBH4-FeCl2-mediated reduction showed high chemoselec...

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Bibliographic Details
Main Authors: Zi-Hong Zhou, Yong-Bo Xu, Shu-Ming Wu, Wei-Jian Ling, Lei Zhang, Zhong-Qing Wang
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2022-09-01
Series:Pharmaceutical Fronts
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1756457