In vivo mutagenicity assessment of orally treated tert-butyl hydroperoxide in the liver and glandular stomach of MutaMouse

In vivo mutagenicity assessment of orally treated tert-butyl hydroperoxide in the liver and glandular stomach of MutaMouse

Abstract Background tert-Butyl hydroperoxide (TBHP; CAS 75–91-2), a hydroperoxide, is mainly used as a polymerization initiator to produce polyethylene, polyvinyl chloride, and unsaturated polyester. It is a high-production chemical, widely used in industrial countries, including Japan. TBHP is also...

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Main Authors: Yasumasa Murata, Kenichiro Suzuki, Yoshiyuki Shigeta, Takako Iso, Nozomu Hirose, Takaaki Umano, Katsuyoshi Horibata, Kei-ichi Sugiyama, Akihiko Hirose, Kenichi Masumura, Mariko Matsumoto
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Genes and Environment
Subjects:
TG488
MutaMouse
TBHP
In vivo mutagenicity
Transgenic rodent gene mutation assay
Online Access:https://doi.org/10.1186/s41021-023-00285-2

Internet

https://doi.org/10.1186/s41021-023-00285-2

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