Emerging mechanisms of pyroptosis and its therapeutic strategy in cancer
Abstract Pyroptosis, a type of inflammatory programmed cell death, is triggered by caspase cleavage of gasdermin family proteins. Based on accumulating evidence, pyroptosis is closely associated with tumour development, but the molecular mechanism underlying pyroptosis activation and the signalling...
Main Authors: | , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-07-01
|
Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-022-01101-6 |