Emerging mechanisms of pyroptosis and its therapeutic strategy in cancer

Emerging mechanisms of pyroptosis and its therapeutic strategy in cancer

Abstract Pyroptosis, a type of inflammatory programmed cell death, is triggered by caspase cleavage of gasdermin family proteins. Based on accumulating evidence, pyroptosis is closely associated with tumour development, but the molecular mechanism underlying pyroptosis activation and the signalling...

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Bibliographic Details
Main Authors: Liqing Lu, Ye Zhang, Xuemei Tan, Yulia Merkher, Sergey Leonov, Li Zhu, Yalan Deng, Huajun zhang, Dandan Zhu, Yuying Tan, Ying Fu, Ting Liu, Yongheng Chen
Format: Article
Language:English
Published: Nature Publishing Group 2022-07-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01101-6

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