Systematic fine-mapping of association with BMI and type 2 diabetes at the FTO locus by integrating results from multiple ethnic groups.

Systematic fine-mapping of association with BMI and type 2 diabetes at the FTO locus by integrating results from multiple ethnic groups.

The 16q12.2 locus in the first intron of FTO has been robustly associated with body mass index (BMI) and type 2 diabetes in genome-wide association studies (GWAS). To improve the resolution of fine-scale mapping at FTO, we performed a systematic approach consisting of two parts.The first part is to...

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Bibliographic Details
Main Authors: Koichi Akiyama, Fumihiko Takeuchi, Masato Isono, Sureka Chakrawarthy, Quang Ngoc Nguyen, Wanqing Wen, Ken Yamamoto, Tomohiro Katsuya, Anuradhani Kasturiratne, Son Thai Pham, Wei Zheng, Yumi Matsushita, Miyako Kishimoto, Loi Doan Do, Xiao-Ou Shu, Ananda R Wickremasinghe, Hiroshi Kajio, Norihiro Kato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4076329?pdf=render

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http://europepmc.org/articles/PMC4076329?pdf=render

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