Impaired histone inheritance promotes tumor progression

Abstract Faithful inheritance of parental histones is essential to maintain epigenetic information and cellular identity during cell division. Parental histones are evenly deposited onto the replicating DNA of sister chromatids in a process dependent on the MCM2 subunit of DNA helicase. However, the...

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Bibliographic Details
Main Authors: Congcong Tian, Jiaqi Zhou, Xinran Li, Yuan Gao, Qing Wen, Xing Kang, Nan Wang, Yuan Yao, Jiuhang Jiang, Guibing Song, Tianjun Zhang, Suili Hu, JingYi Liao, Chuanhe Yu, Zhiquan Wang, Xiangyu Liu, Xinhai Pei, Kuiming Chan, Zichuan Liu, Haiyun Gan
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39185-y