Surfactant Protein D Influences Mortality During Abdominal Sepsis by Facilitating Escherichia coli Colonization in the Gut

Surfactant Protein D Influences Mortality During Abdominal Sepsis by Facilitating Escherichia coli Colonization in the Gut

OBJECTIVES:. Determine the role of surfactant protein D (SPD) in sepsis. DESIGN:. Murine in vivo study. SETTING:. Research laboratory at an academic medical center. PATIENTS:. SPD knockout (SPD−/−) and wild-type (SPD+/+) mice. INTERVENTIONS:. SPD−/− and SPD+/+ mice were subjected to cecal ligation a...

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Main Authors: Jack Varon, MD, MBA, Antonio Arciniegas Rubio, MD, Diana Amador-Munoz, MD, Alexis Corcoran, BA, Joseph A. DeCorte, BS, Colleen Isabelle, BA, Miguel Pinilla Vera, MD, Katherine Walker, MD, MSc, Luke Brown, BSc, Manuela Cernadas, MD, Lynn Bry, MD, PhD, Haopu Yang, Georgios D. Kitsios, MD, PhD, Bryan J. McVerry, MD, Alison Morris, MD, MS, Hyunwook Lee, BA, Judie Howrylak, MD, PhD, Joshua A. Englert, MD, Rebecca M. Baron, MD
Format: Article
Language:English
Published: Wolters Kluwer 2022-05-01
Series:Critical Care Explorations
Online Access:http://journals.lww.com/10.1097/CCE.0000000000000699

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http://journals.lww.com/10.1097/CCE.0000000000000699

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