Psilocin acutely alters sleep-wake architecture and cortical brain activity in laboratory mice

Abstract Serotonergic psychedelic drugs, such as psilocin (4-hydroxy-N,N-dimethyltryptamine), profoundly alter the quality of consciousness through mechanisms which are incompletely understood. Growing evidence suggests that a single psychedelic experience can positively impact long-term psychologic...

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Bibliographic Details
Main Authors: Christopher W. Thomas, Cristina Blanco-Duque, Benjamin J. Bréant, Guy M. Goodwin, Trevor Sharp, David M. Bannerman, Vladyslav V. Vyazovskiy
Format: Article
Language:English
Published: Nature Publishing Group 2022-02-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-01846-9