Brucella MucR acts as an H-NS-like protein to silence virulence genes and structure the nucleoid

Brucella MucR acts as an H-NS-like protein to silence virulence genes and structure the nucleoid

ABSTRACTHistone-like nucleoid structuring (H-NS) and H-NS-like proteins serve as global gene silencers and work with antagonistic transcriptional activators (counter-silencers) to properly coordinate the expression of virulence genes in pathogenic bacteria. In Brucella, MucR has been proposed as a n...

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Bibliographic Details
Main Authors: Ian S. Barton, Zhongqing Ren, Connor B. Cribb, Joshua E. Pitzer, Ilaria Baglivo, Daniel W. Martin, Xindan Wang, R. Martin Roop
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:mBio
Subjects:
MucR
Brucella
virulence
H-NS
H-NS-like
counter-silencer
Online Access:https://journals.asm.org/doi/10.1128/mbio.02201-23

Internet

https://journals.asm.org/doi/10.1128/mbio.02201-23

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