Generation of a TAB2 knockout hESC line (WAe009-A-Z) derived from H9 using CRISPR/Cas9

Generation of a TAB2 knockout hESC line (WAe009-A-Z) derived from H9 using CRISPR/Cas9

TGF-β-activated kinase 1 binding protein 2 (TAB2) is an intermediate protein that connects TNFR1 and other receptor signals to the TGF-β-activated kinase 1 (TAK1) signaling complex. TAB2 has been proved clinically relevant to congenital heart defects (CHD) and cardiomyopathy. In this study, we creat...

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Bibliographic Details
Main Authors: Wenrui Sun, Xiaowei Li, Jianzeng Dong, Yangfan Zhou
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Stem Cell Research
Subjects:
TAB2
CRISPR/Cas9
Gene knockout
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506123002702

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http://www.sciencedirect.com/science/article/pii/S1873506123002702

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