Definition of herpes simplex virus type 1 helper activities for adeno-associated virus early replication events.

The human parvovirus Adeno-Associated Virus (AAV) type 2 can only replicate in cells co-infected with a helper virus, such as Adenovirus or Herpes Simplex Virus type 1 (HSV-1); whereas, in the absence of a helper virus, it establishes a latent infection. Previous studies demonstrated that the ternar...

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Bibliographic Details
Main Authors: Nathalie Alazard-Dany, Armel Nicolas, Aurélie Ploquin, Regina Strasser, Anna Greco, Alberto L Epstein, Cornel Fraefel, Anna Salvetti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2650098?pdf=render