Btk Inhibitors: A Medicinal Chemistry and Drug Delivery Perspective

In the past few years, Bruton’s tyrosine Kinase (Btk) has emerged as new target in medicinal chemistry. Since approval of ibrutinib in 2013 for treatment of different hematological cancers (as leukemias and lymphomas), two other irreversible Btk inhibitors have been launched on the market. In the at...

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Bibliographic Details
Main Authors: Chiara Brullo, Carla Villa, Bruno Tasso, Eleonora Russo, Andrea Spallarossa
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/14/7641