High-frequency irreversible electroporation improves survival and immune cell infiltration in rodents with malignant gliomas

High-frequency irreversible electroporation improves survival and immune cell infiltration in rodents with malignant gliomas

BackgroundIrreversible electroporation (IRE) has been previously investigated in preclinical trials as a treatment for intracranial malignancies. Here, we investigate next generation high-frequency irreversible electroporation (H-FIRE), as both a monotherapy and a combinatorial therapy, for the trea...

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Bibliographic Details
Main Authors: Sabrina N. Campelo, Melvin F. Lorenzo, Brittanie Partridge, Nastaran Alinezhadbalalami, Yukitaka Kani, Josefa Garcia, Sofie Saunier, Sean C. Thomas, Jonathan Hinckley, Scott S. Verbridge, Rafael V. Davalos, John H. Rossmeisl
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Oncology
Subjects:
glioblastoma
intracranial
electroporation
blood-brain barrier disruption
immune response
numerical modeling
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1171278/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1171278/full

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