Pharmacological Approaches for the Modulation of the Potassium Channel K<sub>V</sub>4.x and KChIPs

Pharmacological Approaches for the Modulation of the Potassium Channel K<sub>V</sub>4.x and KChIPs

Ion channels are macromolecular complexes present in the plasma membrane and intracellular organelles of cells. Dysfunction of ion channels results in a group of disorders named channelopathies, which represent an extraordinary challenge for study and treatment. In this review, we will focus on volt...

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Bibliographic Details
Main Authors: Pilar Cercós, Diego A. Peraza, Angela de Benito-Bueno, Paula G. Socuéllamos, Abdoul Aziz-Nignan, Dariel Arrechaga-Estévez, Escarle Beato, Emilio Peña-Acevedo, Armando Albert, Juan A. González-Vera, Yoel Rodríguez, Mercedes Martín-Martínez, Carmen Valenzuela, Marta Gutiérrez-Rodríguez
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
voltage-gated potassium channels K<sub>V</sub>4
transient outward current
A-type current
potassium channel interacting proteins (KChIPs)
protein–protein interactions
K<sub>V</sub>4/KChIPs modulators
Online Access:https://www.mdpi.com/1422-0067/22/3/1419

Internet

https://www.mdpi.com/1422-0067/22/3/1419

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