The Mechanism of Chromatin Remodeler SMARCAD1/Fun30 in Response to DNA Damage

DNA packs into highly condensed chromatin to organize the genome in eukaryotes but occludes many regulatory DNA elements. Access to DNA within nucleosomes is therefore required for a variety of biological processes in cells including transcription, replication, and DNA repair. To cope with this prob...

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Bibliographic Details
Main Authors: Ze-Bin Tong, Hua-Song Ai, Jia-Bin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.560098/full