MMP-9 release into collateral blood vessels before endovascular thrombectomy to assess the risk of major intracerebral haemorrhages and poor outcome for acute ischaemic stroke: a proof-of-concept studyResearch in context

MMP-9 release into collateral blood vessels before endovascular thrombectomy to assess the risk of major intracerebral haemorrhages and poor outcome for acute ischaemic stroke: a proof-of-concept studyResearch in context

Summary: Background: Matrix metalloproteinases (MMPs) are implied in blood–brain barrier degradation and haemorrhagic transformation following ischaemic stroke, but their local relevance in the hyperacute disease phase is unknown. We aimed to examine ultra-early MMP-9 and MMP-2 release into collate...

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Bibliographic Details
Main Authors: Alexander M. Kollikowski, Mirko Pham, Alexander G. März, Jörn Feick, Marius L. Vogt, Yanyan Xiong, Marc Strinitz, Christoph Vollmuth, Fabian Essig, Hermann Neugebauer, Karl Georg Haeusler, Christian Hametner, Lena Zimmermann, Guido Stoll, Michael K. Schuhmann
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:EBioMedicine
Subjects:
Stroke
Ischaemic stroke
Large-vessel occlusion
Matrix metalloproteinases
MMP-9
MMP-2
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424001300

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http://www.sciencedirect.com/science/article/pii/S2352396424001300

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