Determination of a distinguished interferon gamma epitope recognized by monoclonal antibody relating to autoantibody associated immunodeficiency

Determination of a distinguished interferon gamma epitope recognized by monoclonal antibody relating to autoantibody associated immunodeficiency

Abstract Anti-interferon gamma autoantibodies (anti-IFN-γ autoAbs) neutralize the IFN-γ-mediated functions, contributing to immunodeficiency. A particular autoAb in patient serum had been previously demonstrated to recognize the same determinant on IFN-γ as the neutralizing anti-IFN-γ monoclonal ant...

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Bibliographic Details
Main Authors: Umpa Yasamut, Tanchanok Wisitponchai, Vannajan Sanghiran Lee, Montarop Yamabhai, Kuntalee Rangnoi, Weeraya Thongkum, Koollawat Chupradit, Chatchai Tayapiwatana
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-11774-9

Internet

https://doi.org/10.1038/s41598-022-11774-9

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