Unravelling the Distinct Effects of Systolic and Diastolic Blood Pressure Using Mendelian Randomisation

Unravelling the Distinct Effects of Systolic and Diastolic Blood Pressure Using Mendelian Randomisation

A true discrepancy between the effect of systolic blood pressure (SBP) and diastolic blood pressure (DBP) on cardiovascular (CV) outcomes remains unclear. This study performed two-sample Mendelian randomization (MR) using genetic instruments that exclusively predict SBP, DBP or both to dissect the i...

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Bibliographic Details
Main Authors: Nhu Ngoc Le, Tran Q. B. Tran, Stefanie Lip, Linsay McCallum, John McClure, Anna F. Dominiczak, Dipender Gill, Sandosh Padmanabhan
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Genes
Subjects:
blood pressure
systolic
diastolic
Mendelian randomization
Online Access:https://www.mdpi.com/2073-4425/13/7/1226

Internet

https://www.mdpi.com/2073-4425/13/7/1226

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