Defining the Molecular Blueprint that Drives CD8+ T cell Differentiation in response to infection.

A cardinal feature of adaptive, cytotoxic T lymphocyte (CTL)-mediated immunity is the ability of naïve CTLs to undergo a program of differentiation and proliferation upon activation resulting in the acquisition of lineage-specific T cell functions and eventual establishment of immunological...

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Bibliographic Details
Main Authors: Stephen J Turner, Brendan E Russ, Alice E Denton, Lauren eHatton, Hayley eCroom, Matthew R Olson
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00371/full