Staphylococcal β-Toxin Modulates Human Aortic Endothelial Cell and Platelet Function through Sphingomyelinase and Biofilm Ligase Activities

Staphylococcal β-Toxin Modulates Human Aortic Endothelial Cell and Platelet Function through Sphingomyelinase and Biofilm Ligase Activities

ABSTRACT Staphylococcus aureus causes many infections, such as skin and soft tissue, pneumonia, osteomyelitis, and infective endocarditis (IE). IE is an endovascular infection of native and prosthetic valves and the lining of the heart; it is characterized by the formation of cauliflower-like “veget...

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Bibliographic Details
Main Authors: Alfa Herrera, Katarina Kulhankova, Vijay K. Sonkar, Sanjana Dayal, Aloysius J. Klingelhutz, Wilmara Salgado-Pabón, Patrick M. Schlievert
Format: Article
Language:English
Published: American Society for Microbiology 2017-05-01
Series:mBio
Subjects:
beta-toxin
biofilm ligase
sphingomyelinase
Staphylococcus aureus
endothelial cells
Online Access:https://journals.asm.org/doi/10.1128/mBio.00273-17

Internet

https://journals.asm.org/doi/10.1128/mBio.00273-17

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