Immunostaining Protocol: P-Smad2 (Xenograft and Mice)

Immunostaining Protocol: P-Smad2 (Xenograft and Mice)

Metastasis depends on a gene program expressed by the tumor microenvironment upon TGF-beta stimulation. CRC (Colorectal cancer) cell lines did not induce robust stromal TGF-beta responses when injected into nude mice as shown by lack of p-SMAD2 accumulation in tumor-associated stromal cells. To enfo...

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Bibliographic Details
Main Authors: Alexandre Calon, Elisa Espinet, Sergio Palomo-Ponce, Daniele Tauriello, Mar Iglesias, María Céspedes, Marta Sevillano, Cristina Nadal, Peter Jung, Xiang Zhang, Daniel Byrom, Antoni Riera, David Rossell, Ramón Mangues, Joan Massague, Elena Sancho, Eduard Batlle
Format: Article
Language:English
Published: Bio-protocol LLC 2014-05-01
Series:Bio-Protocol
Online Access:https://bio-protocol.org/en/bpdetail?id=1119&type=0

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https://bio-protocol.org/en/bpdetail?id=1119&type=0

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