Identification of genes contributing to cisplatin resistance in osteosarcoma cells

Identification of genes contributing to cisplatin resistance in osteosarcoma cells

Osteosarcomas are prevalent in children and young adults and have a high recurrence rate. Cisplatin, doxorubicin, and methotrexate are common adjuvant chemotherapy drugs for treatment of osteosarcoma, but multidrug resistance is a growing problem. Therefore, understanding the molecular mechanisms of...

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Bibliographic Details
Main Authors: Mingzhong Xie, Haoping Dai, Qingwen Gu, Changming Xiao, Haozhong Wang, Yang Lei, Chunxiao Wu, Xuening Li, Birong Lin, Sen Li
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:FEBS Open Bio
Subjects:
chemotherapy
cisplatin
genetic screen
osteosarcoma
piggyBac transposon
resistance
Online Access:https://doi.org/10.1002/2211-5463.13524

Internet

https://doi.org/10.1002/2211-5463.13524

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