Identification of genes contributing to cisplatin resistance in osteosarcoma cells

Identification of genes contributing to cisplatin resistance in osteosarcoma cells

Osteosarcomas are prevalent in children and young adults and have a high recurrence rate. Cisplatin, doxorubicin, and methotrexate are common adjuvant chemotherapy drugs for treatment of osteosarcoma, but multidrug resistance is a growing problem. Therefore, understanding the molecular mechanisms of...

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Bibliographic Details
Main Authors:	Mingzhong Xie, Haoping Dai, Qingwen Gu, Changming Xiao, Haozhong Wang, Yang Lei, Chunxiao Wu, Xuening Li, Birong Lin, Sen Li
Format:	Article
Language:	English
Published:	Wiley 2023-01-01
Series:	FEBS Open Bio
Subjects:	chemotherapy cisplatin genetic screen osteosarcoma piggyBac transposon resistance
Online Access:	https://doi.org/10.1002/2211-5463.13524

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